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Dr. Reena V Saini

Assistant Professor
Faculty of Applied Sciences & Biotechnology

Assistant Professor at the School of Biotechnology, Shoolini University Dr. Reena V Saini teaches Animal Biotechnology, Stem cell technology and Immunology. She has qualified NET and was awarded by CSIR-Junior Research Fellowship. Worked as visiting fellow at National Cancer Institute, National Institutes of Health, USA, she received her PhD from University of Delhi in Biomedical Sciences. Currently working on Cancer Immunotherapy and Nano-oncology.

  1. Chopra P., Singh B., Singh R., Vohra R., Koul A., Meena L.S., Koduri H., Ghildiyal M., Deol P., Das T.K., Tyagi A.K.,& Singh Y. (2003). Phosphoprotein phosphatase of Mycobacterium tuberculosis dephosphorylates serine-threonine kinases PknA and PknB. Biochemical Biophysics Research Communications. 311, 112-20. doi.org/10.1016/j.bbrc.2003.09.173
  2. Saini A.K., Maithal K., Chand P., Chowdhury S., Vohra R., Goyal A., Dubey G.P., Chopra P., Chandra R., Tyagi A.K., Singh Y.,&Tandon V. (2004) Nuclear localization and in situ DNA damage by Mycobacterium tuberculosis nucleoside-diphosphate kinase. Journal of Biological Chemistry. 79, 50142-9. DOI: 10.1074/jbc.M409944200.
  3. Deol P., Vohra R., Saini A.K., Singh A., Chandra H., Chopra P., Das T.K., Tyagi A.K.,& Singh Y. (2005). Role of Mycobacterium tuberculosis Ser/Thr kinase PknF: implications in glucose transport and cell division. Journal of Bacteriology 187, 3415-20. DOI: 10.1128/JB.187.10.3415-3420.2005.
  4. Vohra R., Gupta M.,& Singh Y. (2006). Attack on the scourge of tuberculosis: Patented drug targets. Recent Patents on Anti-Infective Drug Discovery. 1, 95-106.DOI : 10.2174/157489106775244127.
  5. Rao A., Ram G., Saini A.K., Vohra R., Kumar K., Singh Y.,&Ranganathan A. (2007). Synthesis and selection of de novo proteins that bind and impede cellular functions of an essential mycobacterial protein. Applied and Environmental Microbiology. 73, 1320-31.doi: 10.1128/AEM.02461-06
  6. Saini R.V., Wilson C., Finn M.W., Wang T., Krensky A.M.,&Clayberger C. (2011).Granulysin delivered by cytotoxic cells damages endoplasmic reticulum and activates caspase-7 in target cells. Journal of Immunology.186, 3497-3504. DOI: 10.1128/AEM.02461-06
  7. Clayberger C., Finn M.W., Wang T., Saini R.V., Wilson C., Barr V.A., Sabatino M., Castiello L., Stroncek D.,& Krensky A.M. (2012). 15 kDagranulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity. Journal of Immunology. 188, 6119-6126.DOI: 10.4049/jimmunol.1200570
  8. Kaushal S., Gupta A.,& Saini R.V. (2015) Immunomodulatory activity of in vitro propagated tissues of GentianakurooRoyle. International Journal of Biology, Pharmacy and Allied Sciences. 4, 1873-1886.
  9. Devi U., Indu K., Saini R.V., Navinder K., Andrés G., Srikrishna S., Deepak S., &SainiA.K. (2015). Genomic and Functional Characterization of a Novel Burkholderia sp. Strain AU4i from Pea Rhizosphere Conferring Plant Growth Promoting Activities. Advancements in Genetic Engineering. 4, 129-136.DOI: 10.4172/2169-0111.1000129
  10. Gupta H., Saini R.V., Pagadala V., Kumar N., Sharma D.K.,& Saini A.K. (2016). Analysis of plant growth promoting potential of endophytes isolated from Echinacea purpurea and Lonicera japonica. Journal of Soil Science and Plant Nutrition.169, 558-577. http://dx.doi.org/10.4067/S0718-95162016005000025.
  11. Gupta A., Kumar S., Mahindroo N.,& Saini R.V. (2016). Bioactive Fraction from Datura stramonium Linn. Promotes Human immune Cells Mediated Cytotoxicity towards Lung and Breast Cancer Cells. Pharmacognosy Journal, 8, 435-439.DOI:10.5530/pj.2016.5.4
  12. Chandan G., Chahal A., Saini A.K.& Saini R.V. (2016). Comparative analysis of the antioxidant and immunomodulatory potential of the fractions from leaves of Ocimum spp. (O. sanctum, O. basilicum, O. gratissimum). International Journal of Biology, Pharmacy and Allied Sciences.  2016, 5(11): 2901-2917.
  13. Sharma R., Chandan G., Chahal A.K.,& Saini R. V. (2017). Antioxidant and anticancer activity of methanolic extract from Stephaniaelegans. International Journal of Pharmacy and Pharmaceutical Sciences. 9, 245-249.DOI: 10.22159/ijpps.2017v9i2.16204.
  14. Sharma J., Saini A.K., Kumari R., Hira I., Chahal A.K.,& Saini R.V. (2017). Screening of free radical scavenging, anticancer potential and GC-MS analysis of Trigonellafoenumgraecum leaves. International Journal of Pharmaceutical Science Review and Research. 44, 82-87.
  15. Kumar A., Kumar A., Sharma G., Naushad M., Florian J.S., Ayman A.G., Dhiman P.,& Saini R.V. (2017). Sustainable nano-hybrids of magnetic biochar supported g-C3N4/FeVO4 for solar powered degradation of noxious pollutants- Synergism of adsorption, photocatalysis& photo-ozonation. Journal of Cleaner Production. 165, 431-451.DOI: 10.1016/j.jclepro.2017.07.117
  16. Kumar S., Saini R.V.,&Mahindroo N. (2017). Recent advances in cancer immunology and immunology-based anticancer therapies. Biomedicine & Pharmacotherapy. 96, 1491-1500.https://doi.org/10.1016/j.biopha.2017.11.126
  17. Hira I., Kumari R., Kandwal P., Raj U.L.,& Saini R.V. (2018). Inspection and remedy for cervical cancer using nanoparticles. Nanoscience and Nanotechnology-Asia. 8, 186-192.DOI 10.2174/2210681207666170323155831
  18. Chahal A.K., Saini A.K., Chhillar A.K.,& Saini R.V. (2018). Natural antioxidants as defence system against cancer. Asian Journal of Pharmacy and Clinical Research. 11, 1-7.doi:10.22159/ajpcr.2018.v11i5.24119.
  19. Sharma G., Naushad M., Thakur B., Kumar A., Saini R.V., Chahal A.K., Kumar A., Stadler F.J., Negi P., & Aqil U.M. H. (2018). Sodium Dodecyl Sulphate-Supported Nanocomposite as Drug Carrier System for controlled Delivery of Ondansetron. International Journal of Environmental Research and Public Health.15(3): 414. doi: 10.3390/ijerph15030414.
  20. Hira I., Kumar A., Kumari A., Saini A.K.,& Saini R.V. (2018). Pectin-guar gum-zinc oxide nanocomposite enhances human lymphocytes cytotoxicity towards lung and breast carcinomas. Materials Science and Engineering:C. 90, 494-503.https://doi.org/10.1016/j.msec.2018.04.085
  21. Kumar A., Saini R.V.,& Saini A.K. (2018). Neuroprotective role of ascorbic acid: antioxidant and non-antioxidant functions. Asian Journal of Pharmaceutical and clinical research. 11, 30-33.doi:10.22159/ajpcr.2018.v11i10.27318
  22. Mohammad A., Kumar R.,Thakur P., Rastogi Y.R., Saini R.V., & Saini A.K. (2019). Biological markers for the effects of Yoga as a complementary and alternative medicine.  The Journal of alternative and complementary medicine. (In press).
  23. Saini R.V. &Kumari R. (2017). Nanomaterials enabled immunotherapeutic applications. Springer Nature Singapore Pte Ltd. Metabolic Engineering for Bioactive Compounds, 319-329. doi 10.1007/978-981-10-5511-9_3
  24. Khatri S., Saini R.V.&Chhillar A.K. (2017). Molecular farming approach towards bioactive compound. Springer Nature Singapore Pte Ltd. Metabolic Engineering for Bioactive Compounds, 49-72. doi10.1007/978-981-10-5511-9_3
  25. Phougat N., Kumar M., Saini R.V.&Chhillar A.K. (2017). Green Chemistry approach towards nanoparticle synthesis. Springer Nature Singapore Pte Ltd. Metabolic Engineering for Bioactive Compounds. 249-268. doi 10.1007/978-981-10-5511-9_3
  26. Saini A.K., Gupta H.,Poswal A.M., Kumari R., Kumar R. & Saini R.V. (2017).  Biological Traits of Nanocomposites: Nanofertilizers, Nanopesticides, Anticancer and Antimicrobials. In Modified Biopolymers: Challenges and Opportunities. Nova Science Publishers, Inc. Hauppauge NY, USA.189-206.
  27. Saini A.K., Rastogi Y.R.& Saini R.V. (2018) Advances in Directional Delivery of DNA, siRNA and proteins, In Advances in Polymers for Biomedical Applications. Nova Science Publishers, Inc., New York. Chapter 7

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